Catheter-associated urinary tract infections (CAUTIs) are the most prevalent healthcare-associated infections worldwide, contributing to increased morbidity, mortality, and healthcare costs. Despite the emergence of innovative technologies aimed at CAUTI prevention, their integration into African healthcare systems remains limited due to cost constraints, regulatory gaps, and insufficient local evidence. This narrative review synthesizes recent advancements in CAUTI prevention, evaluates their mechanisms and evidence base, and explores their applicability in low- and middle-income countries (LMICs), with a focus on Nigeria. A comprehensive literature search was conducted across ten databases, PubMed, Web of Science, CINAHL, IEee Xplore, Proquest, Acm Digital Library, Paperity, Public Library of Science, Ebscohost, and Jstor, Covering Publications from January 2015 to July 2025. Peer reviewed studies addressing CAUTI prevention technologies, risk factors, or nursing interventions were included. non-english Articles And Studies Unrelated To Urinary Catheter Infections Were Excluded. Data were extracted narratively and organized by intervention type, mechanism of action, evidence source, and regulatory status. Thirty-eight studies met the inclusion criteria, comprising 16 human trials, 12 laboratory investigations, and 10 animal model studies. Findings of this study show that adherence to aseptic protocols can significantly reduce CAUTI incidence and that silver alloy catheters demonstrated the strongest clinical evidence, while enzyme-responsive and hydrogel technologies remain in preclinical stages. Innovations included metal-based antimicrobial coatings (silver alloy, zinc oxide), polymer-based anti-adhesive surfaces, infection-responsive hydrogels, and antibiotic impregnated catheters. African-specific data were limited, with no large-scale implementation studies identified. While Several CAUTI prevention technologies Show promise, their adoption in LMICS requires addressing cost-effectiveness, supply chain logistics, and antimicrobial resistance risks. Nurse-led protocols particularly those emphasizing aseptic technique, timely catheter removal, and patient education, offer a practical and impactful complement to technological interventions. Strengthening nursing capacity and contextualizing innovations for resource-limited settings are essential to reducing the CAUTI burden In Africa
- DALHATU, | A. | . | adamudalhatu206@gmail.com | +2348039503072, ADAMU | N | LAWAN | nuhulawan7@gmail.com | 07034725303, ADAMU | ALHAJI | . | adamu.alhaji@fuhsa.edu.ng | 08065499113, RAJAH | A. | S. | asrajah.nur@buk.efu.ng | 07037550409
- Innovative Strategies; Technologies; Catheter-associated Urinary Tract Infections; Nurse-led Protocol
- INNOVATIVE STRATEGIES AND TECHNOLOGIES IN PREVENTING CATHETER-ASSOCIATED
